A case of neurolymphomatosis

Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122(8):150-153. doi: 10.17116/jnevro2022122081150.

ABSTRACT

OBJECTIVE: To demonstrate the potential of positron emission tomography with ₁₈F-fluorodeoxyglucose in the diagnosis of a rare manifestation of lymphoma - peripheral nerve plexus lesions.

MATERIAL AND METHODS: A 73-year-old female patient with B-cell small cell lymphoma, stage II B complained of progressive weakness in the lower and upper extremities. The patient was referred for ₁₈F-FDG PET/CT to rule out disease progression and evaluate the effectiveness of the treatment.

RESULTS: The diagnosis of neurolymphomatosis was verified. Neurolymphomatosis differs from paraneoplastic, inflammatory, or drug-induced neuropathies both in terms of clinical manifestations and in terms of prognosis. Difficulties in diagnosis lie in the extreme variety of symptoms and the extensive differential diagnosis.

CONCLUSION: ₁₈F-FDG PET/CT is a sensitive method for the diagnosis of neurolymphomatosis.

PMID:36036417 | DOI:10.17116/jnevro2022122081150